Mac ver 2.5

total failure to open any projects or files
trying a re-install

Does the program even open? If not, and if you didn’t download from the Apple app store, you might want to check your security settings is Sys Prefs…

[attachment=0]security.png[/attachment]

Repairing Disk Permissions via Disk Utility might also help.

If you were upgrading…
scrivener.tenderapp.com/help/kb … er-upgrade

A reinstall sounds the best thing to do. Scrivener 2.5 has been in use for a few months now, and there are no known major issues with it, so a bad install seems a good bet.